Liga 1 - Sezon Regular - Meciurile Etapei 13
| Oct 22, 2021 17:30 | U Craiova 1948 SA | 2 - 0 | CS Gaz Metan Mediaş |  |
| Oct 22, 2021 20:30 | AFC Chindia Târgovişte | 0 - 1 | Universitatea Craiova | |
| Oct 23, 2021 15:00 | SC FC Voluntari SA | 0 - 2 | ACS Campionii Fotbal Club Argeş | |
| Oct 23, 2021 17:30 | CS Mioveni | 1 - 1 | AFC Botoşani | |
| Oct 23, 2021 20:30 | SC Dinamo 1948 SA | 1 - 1 | Fotbal Club Rapid 1923 SA | |
| Oct 25, 2021 17:30 | ACS FC Academica Clinceni | 0 - 3 | AFC UTA Arad | |
| Oct 25, 2021 20:30 | FC CFR 1907 Cluj SA | 2 - 0 | ACS Sepsi OSK Sfântu Gheorghe | |
| Nov 4, 2021 00:00 | Farul Constanţa | - | SC Fotbal Club FCSB SA | |
| Loc | Echipa | M | V | E | I | Gol | +/- | Pct |
| 1. | FC CFR 1907 Cluj SA | 13 | 11 | 0 | 2 | 19-8 | 11 | 33 |
| 2. | Universitatea Craiova | 13 | 8 | 1 | 4 | 23-10 | 13 | 25 |
| 3. | SC Fotbal Club FCSB SA | 12 | 7 | 3 | 2 | 23-11 | 12 | 24 |
| 4. | AFC Botoşani | 13 | 6 | 6 | 1 | 13-9 | 4 | 24 |
| 5. | SC FC Voluntari SA | 13 | 8 | 0 | 5 | 17-15 | 2 | 24 |
| 6. | AFC UTA Arad | 13 | 6 | 5 | 2 | 15-8 | 7 | 23 |
| 7. | Fotbal Club Rapid 1923 SA | 13 | 6 | 4 | 3 | 16-10 | 6 | 22 |
| 8. | ACS Campionii Fotbal Club Argeş | 13 | 6 | 3 | 4 | 12-7 | 5 | 21 |
| 9. | Farul Constanţa | 12 | 5 | 3 | 4 | 15-8 | 7 | 18 |
| 10. | AFC Chindia Târgovişte | 13 | 3 | 5 | 5 | 8-9 | -1 | 14 |
| 11. | U Craiova 1948 SA | 13 | 3 | 3 | 7 | 10-14 | -4 | 12 |
| 12. | CS Mioveni | 13 | 3 | 3 | 7 | 7-17 | -10 | 12 |
| 13. | CS Gaz Metan Mediaş | 13 | 3 | 2 | 8 | 10-17 | -7 | 11 |
| 14. | ACS Sepsi OSK Sfântu Gheorghe | 13 | 1 | 7 | 5 | 10-15 | -5 | 10 |
| 15. | SC Dinamo 1948 SA | 13 | 2 | 2 | 9 | 11-29 | -18 | 8 |
| 16. | ACS FC Academica Clinceni | 13 | 0 | 3 | 10 | 9-31 | -22 | 3 |