Liga 2 - Meciurile Etapei 19
| Mar 10, 2022 19:30 | AFC Unirea Constanţa | 2 - 3 | ACS Petrolul 52 |  |
| Mar 12, 2022 14:00 | Politehnica Timișoara | 1 - 2 | AFC Hermannstadt | |
| Mar 12, 2022 14:00 | AS Fotbal Club Buzău | 0 - 1 | CS Concordia Chiajna | |
| Mar 12, 2022 14:00 | ACSM Politehnica Iaşi | 3 - 1 | AFC Astra | |
| Mar 12, 2022 14:00 | FC Metaloglobus Bucureşti | 1 - 3 | Clubul Sportiv al Armatei Steaua | |
| Mar 12, 2022 14:00 | AFK Csikszereda Miercurea Ciuc | 1 - 1 | Fotbal Club Braşov | |
| Mar 12, 2022 14:00 | ACS Viitorul Pandurii Târgu Jiu | 1 - 0 | CSC 1599 Şelimbăr | |
| Mar 12, 2022 14:00 | AFC 1919 Dacia Unirea Brăila | 0 - 1 | FC Unirea Dej | |
| Mar 12, 2022 14:00 | AFC Unirea 04 Slobozia | 1 - 0 | SC Fotbal Club Ripensia Timișoara | |
| Mar 13, 2022 11:30 | AS FC Universitatea Cluj | 3 - 0 | AFC Dunărea 2005 Călăraşi | |
* Clubul AFC Astra a fost sancţionat cu o penalitate de 20 puncte prin deciziile CDE din 16.06.2021, 30.06.2021, 07.07.2021, 14.07.2021, 25.08.2021, 22.09.2021, 22.09.2021 şi 28.01.2022
| Loc | Echipa | M | V | E | I | Gol | +/- | Pct |
| 1. | ACS Petrolul 52 | 19 | 16 | 1 | 2 | 41-7 | 34 | 49 |
| 2. | AS FC Universitatea Cluj | 19 | 14 | 0 | 5 | 34-14 | 20 | 42 |
| 3. | AFC Hermannstadt | 19 | 12 | 5 | 2 | 41-15 | 26 | 41 |
| 4. | Clubul Sportiv al Armatei Steaua | 19 | 11 | 4 | 4 | 31-13 | 18 | 37 |
| 5. | CS Concordia Chiajna | 19 | 10 | 6 | 3 | 18-10 | 8 | 36 |
| 6. | AFC Unirea 04 Slobozia | 19 | 9 | 6 | 4 | 33-13 | 20 | 33 |
| 7. | AFK Csikszereda Miercurea Ciuc | 19 | 10 | 3 | 6 | 32-23 | 9 | 33 |
| 8. | AS Fotbal Club Buzău | 19 | 9 | 5 | 5 | 43-14 | 29 | 32 |
| 9. | FC Unirea Dej | 19 | 8 | 4 | 7 | 17-16 | 1 | 28 |
| 10. | FC Metaloglobus Bucureşti | 19 | 8 | 4 | 7 | 22-23 | -1 | 28 |
| 11. | ACSM Politehnica Iaşi | 19 | 7 | 4 | 8 | 25-21 | 4 | 25 |
| 12. | SC Fotbal Club Ripensia Timișoara | 19 | 6 | 7 | 6 | 18-19 | -1 | 25 |
| 13. | ACS Viitorul Pandurii Târgu Jiu | 19 | 6 | 6 | 7 | 16-20 | -4 | 24 |
| 14. | CSC 1599 Şelimbăr | 19 | 6 | 5 | 8 | 18-26 | -8 | 23 |
| 15. | Politehnica Timișoara | 19 | 6 | 3 | 10 | 19-27 | -8 | 21 |
| 16. | Fotbal Club Braşov | 19 | 3 | 5 | 11 | 16-32 | -16 | 14 |
| 17. | AFC Unirea Constanţa | 19 | 3 | 2 | 14 | 18-54 | -36 | 11 |
| 18. | AFC Dunărea 2005 Călăraşi | 19 | 1 | 4 | 14 | 12-50 | -38 | 7 |
| 19. | AFC 1919 Dacia Unirea Brăila | 19 | 0 | 2 | 17 | 7-53 | -46 | 2 |
| 20. | AFC Astra | 19 | 5 | 4 | 10 | 21-32 | -11 | -1 |